What is the penetration limit for fNIRS in tissue? / How deep can one probe with NIRS?

Light intensity is heavily attenuated in tissue and falls off exponentially from the illumination point. The maximum achievable probing depth of NIRS is limited by the illumination strength – determined by the thermal damaging threshold – and the detection sensitivity. Imaging depth strongly depends on the tissue type and the application. Typical achievable transmission limits of NIRS are about 12 cm for breast tissue, and 6 cm on the arm or leg. For brain imaging, the probing depth of NIRS is about 3 cm.

What is the penetration limit for fNIRS in tissue? / How deep can one probe with NIRS?

Light intensity is heavily attenuated in tissue and falls off exponentially from the illumination point. The maximum achievable probing depth of NIRS is limited by the illumination strength – determined by the thermal damaging threshold – and the detection sensitivity. Imaging depth strongly depends on the tissue type and the application. Typical achievable transmission limits of NIRS are about 12 cm for breast tissue, and 6 cm on the arm or leg. For brain imaging, the probing depth of NIRS is about 3 cm.

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